Which drug class controls hypermotility in IBS?

• A. Anti-infective
• B. Antiretroviral
• C. Antispasmodic
• D. Bone resorption inhibitor

Answer: (C)

Antispasmodics are used to calm the gut by relaxing smooth muscle, which directly reduces the excessive contractions that drive hypermotility in IBS. When the bowel doesn’t spasm as much, cramps lessen and urgency improves, giving symptomatic relief for diarrheal or mixed IBS. Many antispasmodics work by blocking muscarinic receptors in the GI tract or acting as direct smooth muscle relaxants, so they specifically target the motility problem rather than the cause of IBS itself. Other drug classes listed don’t address intestinal smooth muscle spasm: anti-infectives treat infections, antiretrovirals target HIV, and bone resorption inhibitors affect bones. So antispasmodics are the best choice for controlling hypermotility in IBS.