Drugs like INH and others are used in the treatment of tuberculosis; they inhibit growth of mycobacteria. Which pharmacologic class do they belong to?

• A. Antineoplastic
• B. Antitumor Necrosis Factor
• C. Antitussive
• D. Antituberculosis

Answer: (D)

The main idea is recognizing a specific pharmacologic class designed to treat infections caused by Mycobacterium tuberculosis. Drugs in this group, including INH, are tailored to act against mycobacteria and are used in combination to prevent resistance. Isoniazid is a representative member: it is a prodrug activated by the bacterial enzyme KatG, and once activated it blocks the synthesis of mycolic acids, which are essential components of the mycobacterial cell wall. This targeted approach toward mycobacterial physiology is what defines the antituberculosis class. Other drug categories like antineoplastics (cancer therapies), anti-TNF agents (for certain inflammatory conditions), or antitussives (cough suppressants) don’t act on Mycobacterium tuberculosis, so they don’t belong to this TB-specific class.